Tetrandrine 98%

98% High purity Tetrandrine extracted from Stephania Tetrandra. Anti-inflammatory & anti-tumor. Pharma & cosmetic grade, bulk supply & OEM available.

  • Shelf Life: 24 months (Sealed, stored away from light, cool and dry place)
  • Packaging: 1kg aluminum foil bag, 25kg fiber drum with inner PE bag, customized packaging supported
  • Services: Bulk supply, formula customization, OEM/ODM, third-party testing support

Tetrandrine 98% | Stephania Tetrandra Extract Raw Material

Tetrandrine 98% Extract Features
  • Product Name: Tetrandrine 98%, also known as Fangchinoline A
  • Latin Name: Stephania Tetrandra S. Moore
  • Raw Material Source: Dried tuberous root of Stephania Tetrandra, authentic medicinal herb raw material
  • Core Active Ingredient: Tetrandrine, a type of dibenzylisoquinoline alkaloid
  • Specification: ≥98% (Tested by HPLC)
  • CAS No.: 518-34-3
  • Appearance: White to off-white crystalline powder, odorless and tasteless
  • Solubility: Freely soluble in chloroform, soluble in ethanol and methanol, slightly soluble in ether, practically insoluble in water
  • Test Method: High Performance Liquid Chromatography (HPLC)
  • Grade: Pharmaceutical grade, Cosmetic grade, Research grade
  • Certifications: ISO22000, cGMP, SGS third-party test reports
  • Mesh Size: 80–100 mesh, customized ultra-fine powder available
  • MOQ: 1 KG
  • Free Sample: 5–20g for R&D and formula testing

Detailed Introduction of Tetrandrine Product

Tetrandrine is a high-activity natural alkaloid extracted and purified from the dried tuberous root of authentic Stephania Tetrandra, and it is the most dominant functional component of this traditional medicinal herb. Our 98% Tetrandrine is produced by the combined process of acid-water extraction, organic solvent extraction and preparative chromatography. The whole production complies with cGMP standards. Impurities, heavy metals and residual solvents are strictly removed. The finished product features stable purity and tiny batch variation, complying with the Pharmacopoeia standards of China, Europe, the United States and global pharmaceutical raw material access requirements.

As a classic dibenzylisoquinoline alkaloid, 98% Tetrandrine has diverse biological activities. It is a popular raw material for biomedicine, cosmetic skincare, new drug research and functional health products. In the pharmaceutical industry, Tetrandrine shows outstanding anti-inflammatory, analgesic, anti-fibrotic and anti-tumor effects, widely applied in the development of preparations for rheumatoid pain, neuralgia, silicosis and adjuvant tumor treatment. In the cosmetic industry, Tetrandrine can relieve skin inflammation, soothe sensitive skin, resist oxidation and photodamage, and is widely used in high-end repair, anti-allergy and anti-aging skincare products. Besides, it serves as standard reference substance and experimental material for pharmacological tests and new drug screening in universities and research institutions worldwide.

We supply 98% Tetrandrine in pharmaceutical grade, cosmetic grade and research grade. Customization on particle size, solvent residue and microbial indicators is available. Complete HPLC chromatogram, COA, MSDS and full qualification documents are provided for each batch. We deliver one-stop services for global pharmaceutical enterprises, cosmetic manufacturers, research institutes and raw material traders.

Core Efficacy of Tetrandrine

Powerful Anti-Inflammatory & Analgesic Effect

Tetrandrine inhibits the release of inflammatory factors, relieves joint pain, neuralgia and rheumatic pain, acting as a core active raw material for rheumatism preparations.

Anti-Fibrosis Activity

It has a remarkable improvement effect on pulmonary fibrosis, widely used in the R&D and production of medicines for silicosis and coal silicosis.

Anti-Tumor Adjuvant Effect

It reverses multidrug resistance of tumor cells and enhances the sensitivity to radiotherapy and chemotherapy, used as an adjuvant raw material for tumor treatment.

Antioxidant & Repairing Function

Scavenges free radicals, reduces oxidative damage and delays cell aging, suitable for anti-aging cosmetics and health products.

Skin Soothing & Anti-Allergy

Relieve skin inflammation, redness, stinging and sensitivity, ideal for sensitive skin repair formulas.

Cardiovascular Protection

Dilates coronary vessels, regulates blood pressure and inhibits platelet aggregation, applied in the development of cardiovascular pharmaceutical raw materials.

Antibacterial Property

Inhibits a variety of pathogenic bacteria, suitable for external disinfection and antibacterial skincare formulas.

Immunomodulation

Bidirectionally regulates human immune function and optimizes immune status, used for conditioning health raw materials.

Core Advantages of Tetrandrine Product

Stable High Purity

Tetrandrine content is steadily over 98% with full HPLC inspection. Batch variation is less than 1%, meeting strict standards of high-end pharmaceuticals and scientific research.

Traceable Authentic Raw Materials

Adopt standardized cultivated Stephania Tetrandra tuberous roots with full traceability. The natural active content is higher than common raw materials.

Exclusive Purification Technology

Adopt chromatographic refining technology. Impurities, residual solvents and heavy metals are strictly controlled to comply with USP and EP pharmacopoeia.

Multi-Grade Customization

Pharmaceutical grade, cosmetic grade and research grade are available. Microorganism, solubility and powder indicators can be adjusted on demand.

Low Impurity & High Safety

Heavy metal, pesticide residue and microbe are strictly controlled without artificial additives, suitable for export to Europe, America and Southeast Asia.

Excellent Powder Performance

Crystalline powder has good fluidity and compatibility, suitable for tablets, capsules, injections, skincare creams and multiple dosage forms.

Complete Document Support

COA, HPLC, MSDS and third-party test reports are provided per batch, supporting export customs clearance and product registration.

One-Stop Servic

Cover sample testing, mass production, formula compounding and private label OEM. Professional technical support team is available all the time.

Detailed Quality Inspection Standards of Tetrandrine

Test ItemStandard Requirement
Tetrandrine Content (HPLC)≥98.0%
AppearanceWhite to off-white crystalline powder
Loss on Drying≤1.0%
Residue on Ignition≤0.2%
Total Heavy Metals≤10ppm
Lead (Pb)≤2.0ppm
Arsenic (As)≤1.0ppm
Cadmium (Cd)≤1.0ppm
Mercury (Hg)≤0.1ppm
Residual SolventsCompliant with USP / EP Standards
Total Plate Count≤1000 CFU/g (Pharmaceutical Grade)
Yeast & Mold≤100 CFU/g
Pathogenic Bacteria (Salmonella, E.coli)Negative

Application Fields & Recommended Dosage of Tetrandrine

Pharmaceutical Preparations:

Used for anti-rheumatic, anti-fibrosis and tumor adjuvant drugs. Regular dosage for oral preparations: 20–100mg per time, injections comply with pharmacopoeia standards.

Cosmetics & Skincare:

Dosage: 0.01%–0.1%. Applied in soothing, anti-inflammatory, anti-aging serums, creams and facial masks.

Scientific Research:

Used as standard reference substance and experimental material for new drug screening and pharmacological mechanism research in universities and pharmaceutical enterprises.

Functional Health Products:

Added to joint care and immune regulation dietary supplements with customized dosage.

External Antibacterial Products:

Used in external ointments and lotions to relieve skin discomfort with antibacterial and anti-inflammatory properties.

Production Process of Tetrandrine

What we offer

Supporting Services

We provide full-chain services of Tetrandrine for global pharmaceutical, cosmetic and research clients: 5–20g free test samples are available; 1kg trial orders and large bulk orders are supported; Custom purity, particle size and packaging are acceptable; Provide formula guidance and compliance consultation; Support OEM/ODM and compound raw material processing; Complete test reports and qualification documents are delivered with each batch.
Common Questions

FAQ About Tetrandrine Extract

What is the difference between 98% Tetrandrine and common Stephania Tetrandra extract?
98% Tetrandrine is monomer alkaloid purified by multi-stage chromatography with single and precise composition, mainly used for pharmaceuticals, high-end cosmetics and scientific research. Common extract is total alkaloids with complex components, mostly for ordinary health products.
It is freely soluble in chloroform, ethanol and methanol, practically insoluble in water. Solubility modification with cosolvent or cyclodextrin is available for oral liquid and external liquid formulas.
All indicators meet USP and EP standards. Heavy metals, solvent residues and microorganisms are qualified. Full documents support customs clearance and product registration in Europe and America.
Pharmaceutical grade for drug raw materials and injections; Cosmetic grade for skincare and external products; Research grade for lab reference substances and pharmacological tests.
Will long-term storage affect product purity?
The purity remains stable for 24 months when sealed, protected from light and stored in cool dry place. Please use it as soon as possible after opening to prevent moisture and oxidation.
The purity remains stable for 24 months when sealed, protected from light and stored in cool dry place. Please use it as soon as possible after opening to prevent moisture and oxidation.
We adopt fixed raw material base and standardized production lines. Each batch is fully tested by HPLC. The difference of content and impurities is extremely small for long-term mass production.
Yes. Free samples are provided for third-party testing, and all indicators comply with international standards.