98% High Purity Aescin Escin

Standard Horse Chestnut Extract Aescin | Bulk & Custom Supply

  • Shelf Life: 24 months (Sealed, stored in cool, dry and dark place)
  • Packaging: 1kg aluminum foil bag, 25kg fiber drum with inner PE bag, customized packaging supported
  • Services: Bulk supply, specification customization, OEM/ODM, full test document support

Aescin (Escin) | Horse Chestnut Seed Extract High-Active Triterpene Saponin

98% Aescin Escin Extract Features
  • Product Name: Aescin (Also named Escin, Horse Chestnut Saponin)
  • Common Name: Aescin / Escin
  • Latin Name: Aesculus hippocastanum L.
  • Raw Material Source: Dried mature seeds of Horse Chestnut
  • Core Ingredient: Aescin (Mixture of Aescin A, B, C, D, triterpene saponins)
  • Specification: 20%, 40%, 60%, 90%, 98% (Tested by HPLC)
  • CAS No.: 6805-41-0
  • Appearance: Off-white to pale yellow crystalline powder
  • Solubility: Soluble in methanol, ethanol and dilute alkaline solution, slightly soluble in water
  • Test Method: High Performance Liquid Chromatography (HPLC)
  • Grade: Pharmaceutical grade, Cosmetic grade, Food grade, Research grade
  • Certifications: ISO22000, FSSC22000, cGMP, Halal, Kosher
  • Mesh Size: 80–100 mesh, customized ultra-fine powder available
  • MOQ: 1 KG
  • Free Sample: 5–20g for formula R&D and third-party testing

Detailed Introduction of Aescin Product

Aescin (Escin) is a natural triterpene saponin extracted and purified from the dried seeds of Aesculus hippocastanum, a traditional European medicinal plant. It is a well-developed functional active ingredient widely used in global pharmaceutical, cosmetic and health food industries. We adopt a combined process of low-temperature alcohol extraction, macroporous resin adsorption and preparative chromatography. The whole production complies with cGMP standards, which fully retains the natural activity of aescin. We strictly control solvent residues, heavy metals, microorganisms and pesticide residues. Our products have complete purity grades and ultra-low batch deviation, complying with USP, EP, EU and US food & pharmaceutical regulations.
Composed of synergistic Aescin A, B, C and D, this ingredient has classic pharmacological activities including anti-edema, anti-inflammation and vascular protection. It is a core raw material for clinical treatment of venous insufficiency and soft tissue swelling. In pharmaceutical field, it is widely applied in preparations for edema and inflammation caused by trauma, surgery and varicose veins. In cosmetics, it relieves redness, repairs sensitive skin and improves skin microcirculation, so it is commonly used in leg care, anti-allergy and firming skincare products. Aescin with different purities is also suitable for dietary supplements and laboratory reference substances.
We provide multi-grade and multi-purity aescin according to formula demands. Customization on solubility, particle size and packaging is available. COA, HPLC chromatogram, MSDS and third-party test reports are provided for each batch. We deliver one-stop services for global pharmaceutical enterprises, cosmetic manufacturers, research institutes and raw material traders.

Core Efficacy of Aescin

Powerful Anti-Edema Effect

Inhibit abnormal vascular exudation, accelerate lymph and venous return, and relieve limb edema, postoperative swelling and lower limb swelling rapidly.

Broad-Spectrum Anti-Inflammation

Restrain the release of inflammatory factors, alleviate soft tissue inflammation and phlebitis, and reduce local redness, swelling, heat and pain.

Vascular Function Repair

Enhance the tension and elasticity of venous vessel walls, improve venous insufficiency for varicose vein formulas.

Skin Microcirculation Regulation

Promote blood circulation on skin surface, relieve dullness and soreness, ideal for leg care and skin brightening products.

Skin Soothing & Repair

Relieve redness and sensitivity caused by external irritation, strengthen skin barrier for repair skincare.

Antioxidant Protection

Scavenge free radicals, reduce oxidative damage and delay cell aging.

Core Advantages of Aescin Product

Full Range of High Purity Grades

Aescin from 20% to 98% with full HPLC inspection. Batch deviation is less than 1.5%, matching various formulas and cost budgets.

Authentic European Raw Materials

Imported horse chestnut seeds from Europe with stable component ratio and higher natural activity.

Advanced Purification Technology

Low-temperature extraction and chromatographic refining avoid active degradation. Solvent and pesticide residues meet strict USP & EP standards.

Multi-Grade Compliance

Divided into pharmaceutical, cosmetic, food and research grades. Targeted index control meets global industry access rules.

Excellent Powder Performance

Good fluidity and stable solubility, suitable for tablets, capsules, creams and liquid formulations.

Complete Documents & Services

Full test reports and certifications per batch. Support samples, bulk orders and OEM, with professional technical guidance.

Detailed Quality Standards of Aescin

Test ItemStandard Requirement
Aescin Content (HPLC)As agreed (20%/40%/60%/90%/98%)
AppearanceOff-white to pale yellow crystalline powder
Loss on Drying≤3.0%
Residue on Ignition≤0.5%
Total Heavy Metals≤10ppm
Lead (Pb)≤2.0ppm
Arsenic (As)≤1.0ppm
Cadmium (Cd)≤1.0ppm
Mercury (Hg)≤0.1ppm
Residual SolventsCompliant with USP / EP Standards
Total Plate Count≤1000 CFU/g
Yeast & Mold≤100 CFU/g
Pathogenic Bacteria (Salmonella, E.coli)Negative

Application & Dosage

Pharmaceutical Preparations:

Oral and external products for vascular care, anti-edema and anti-inflammation. Daily oral dosage: 10–50mg, external dosage: 0.2%–1.0%.

Cosmetics:

Leg firming, anti-redness and soothing skincare. Recommended dosage: 0.1%–0.8%.

Dietary Supplements

Capsules & powder for circulation care, dosed according to formulas.

Scientific Research

Pharmacopoeia reference substances and experimental materials for R&D.

External Care Products:

Soothing ointments and sprays, dosage: 0.15%–0.6%.

Production Process of Aescin

What we offer

Supporting Services

We provide one-stop services for global pharmaceutical, cosmetic, food and research clients: 5–20g free samples available; 1kg trial orders and large bulk orders supported; Custom purity, mesh and packaging; Formula guidance and compliance consultation; Compound processing & OEM private label; Complete test reports and certificates provided per batch.
Common Questions

FAQ About Aescin Extract

What is the difference between aescin and common horse chestnut extract?
Aescin is purified saponin with accurate content and stable activity, for pharmaceuticals, high-end cosmetics and research. Common extract has low purity for regular health products.
It is slightly soluble in water. Solubility modification with cosolvent or cyclodextrin is available for oral and external liquids.
All indicators meet USP and EP standards. Complete documents support global customs clearance and registration.
20%/40% for regular health products; 60% for mid-range cosmetics; 90%/98% for pharmaceuticals, premium formulas and research.
Will storage affect aescin activity?
The shelf life is 24 months when sealed, cool and dark. Please use it quickly after opening to prevent moisture and oxidation.
Yes, we can compound aescin with flavonoids and polyphenols to make customized functional raw materials.
Stable European raw material supply and standardized production lines. Full HPLC inspection per batch ensures consistent quality for mass production.
Yes, free samples are provided for third-party testing, fully compliant with international standards.