98% Phloretin | Apple Bark Extract High-Purity Dihydrochalcone Crystalline Powder
98% High Purity Phloretin | Apple-Derived Dihydrochalcone Brightening Penetration Active Monomer
- Product Name: Phloretin (INCI: Phloretin)
- Common Name: Phloretin
- Latin Raw Herb: Malus pumila Mill. (Dried apple bark & peel)
- CAS No.: 60-82-2
- Core Active: Phloretin (Natural lipophilic dihydrochalcone monomer)
- Standard Assay: ≥98% (RP-HPLC-DAD Pharmacopoeia Test)
- Raw Source: Dried bark & peel of standardized eco-cultivated apple trees
- Appearance: Off-white to pale beige acicular crystalline powder, odorless & non-hygroscopic
- Solubility: Freely soluble in ethanol, methanol, ethyl acetate, DMSO; slightly soluble in hot water; barely soluble in cold water & oils
- Extraction & Purification Process: Ethanol reflux extraction → macroporous resin impurity removal → silica gel chromatography → low-temperature vacuum recrystallization
- Test Standards: CP / USP / EP polyphenol determination specifications
- Product Grades: Premium Cosmetic Grade, Pharmaceutical Grade, Research Reference Grade
- International Certifications: ISO22000, FSSC22000, full SGS testing, ECOCERT natural ingredient certificate
- Mesh Size: 80–100 mesh, customized 300 mesh ultra-fine crystal powder available
- MOQ: 1 KG
- Free Sample: 5–30g for formula trial & third-party full pharmacopoeia testing
- Shelf Life: 24 months under sealed refrigeration at 2–8℃, avoid air & light oxidation
Detailed Introduction of Phloretin
Phloretin is exclusive lipophilic dihydrochalcone polyphenol monomer from apples. Different from water-soluble phlorizin, it features outstanding transdermal penetration, making it core high-purity botanical raw material for premium brightening serums, penetration-boosting preparations and metabolic pharmacological research worldwide. We adopt bark & peel from standardized eco apple base, integrated ethanol extraction & multi-stage chromatography recrystallization technology to fully remove interfering tannin, polysaccharide and miscellaneous flavonoids. Finished product delivers pure single HPLC peak with batch fluctuation controlled within 0.3%, fully meeting strict QC requirements of high-end cosmetic brands, oral pharmaceutical factories and university new drug screening.
Phloretin owns rare dual-industry core advantages: For skincare, it provides powerful tyrosinase inhibition, broad-spectrum anti-oxidation and unique penetration enhancement, greatly improving skin absorption of VC, niacinamide, asiaticoside and other actives; For pharma & nutraceuticals, it blocks GLUT glucose transporters to assist glucose metabolism regulation, with anti-inflammation & UV DNA repair activity. Compatible with alcohol serums, ointments, liposomes and oral tablets, it delivers synergistic effects when blended with brightening & repair actives.
The whole closed-loop production runs under low light & low temperature to prevent polyphenol oxidation caused by phenolic hydroxyl groups. Pesticide residues, heavy metals and residual solvents all meet EU & US import limits. Stable ton-level bulk stock with full chromatograms & compliance docs per batch, offering one-stop service for global cosmetic manufacturers, nutraceutical traders and pharmaceutical R&D labs.
Core Efficacy of Phloretin
Potent tyrosinase inhibition to block melanin production & fade sun/ inflammatory pigmentation
Powerful free radical scavenger against UV photoaging & collagen loss
Unique penetration booster to raise transdermal absorption of VC, peptides & asiaticoside
Broad-spectrum anti-inflammation to relieve redness & irritation from acid peeling & sun exposure
Inhibit GLUT transporters to stabilize postprandial blood sugar & regulate glucose metabolism
Natural antibacterial antioxidant as preservative stabilizer for edible oils
Core Advantages of Phloretin
98% recrystallization pure monomer with clean HPLC peak for pharmacopoeia reference calibration
Self-owned eco apple planting base with higher native phloretin content
Lipophilic molecular structure delivers superior penetration boosting over most brightening polyphenols
Low-light closed production prevents polyphenol oxidation & activity loss during long storage
Four-fold strict QC: pesticides, heavy metals, solvents & microbes compliant with EU & US import rules
Full-chain one-stop service: free samples, ton bulk stock, compound OEM & complete certificates
Quality Specifications
| Test Item | Standard Requirement |
|---|---|
| Phloretin Content (HPLC-DAD Pharmacopoeia) | ≥98.0% |
| Appearance | Off-white to pale beige acicular crystalline powder |
| Loss on Drying | ≤2.5% |
| Residue on Ignition | ≤0.2% |
| Total Heavy Metals | ≤10ppm |
| Pb≤2ppm, As≤1ppm, Cd≤1ppm, Hg≤0.1ppm | |
| Residual Organic Solvents | Compliant with USP / EP / CP pharmaceutical raw material limits |
| Total Plate Count | ≤500 CFU/g (Strict pharmaceutical standard) |
| Yeast & Mold | ≤50 CFU/g |
| Salmonella, E.coli: Negative |
Application & Dosage
Premium Brightening Spot Serums:
0.03%–0.15% for melanin inhibition & acne mark fading
Penetration Boost Repair Creams:
0.02%–0.1% improve absorption of compound actives
Anti-Photoaging Sunscreen Formulas:
0.04%–0.18% against UV DNA damage
Glucose Metabolism Nutraceutical Capsules:
100–260mg daily for postprandial care
Natural Food Antioxidant:
0.01%–0.06% for edible oil preservation
Lab Pharmacopoeia Reference Standard:
98% crystal for polyphenol & GLUT target research
Production Process of Phloretin
Constant temperature & low light closed-loop production fully retain native phloretin polyphenol activity, multi-stage impurity removal strictly control all harmful residues.
What we offer
Supporting Services
Common Questions
FAQ About Sponge Phloretin
1. What is the core difference between Phloretin and Phlorizin?
2. Are there special storage requirements for 98% Phloretin?
3. Can this product export to EU & US cosmetic & pharmaceutical manufacturers smoothly?
4. What are three core skincare functions of Phloretin?
5. What is the solubility of Phloretin?
Freely soluble in ethanol & DMSO, barely soluble in cold water, requires alcohol or lipid carrier for formulations.